Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547171 | 0.81 | KDM4E (0.45) | MAPTALDH1A1USP2SMN1; SMN2KDM4E | |
| SCHEMBL5547166 | 0.81 | SMN1; SMN2 (0.39) | MAPTUSP2SMN1; SMN2MCHR1 | |
| SCHEMBL8728925 | 0.80 | ADRB1 (0.46) | MAPTKMT2AALDH1A1MEN1GPR119 | |
| SCHEMBL8728922 | 0.78 | L3MBTL3 (0.37) | MAPTKMT2AUSP2SMN1; SMN2KDM4E | |
| SCHEMBL520505 | 0.78 | MAPT (0.53) | MAPTKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL23388730 | 0.78 | MAPT (0.59) | MAPTKMT2AALDH1A1MEN1GPR119 | |
| SCHEMBL8260715 | 0.78 | USP2 (0.75) | MAPTKMT2AALDH1A1MEN1GPR119 | |
| SCHEMBL27995386 | 0.78 | CHRNA7 (0.50) | KMT2AMEN1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL334359 | 0.78 | MAPT (0.59) | MAPTKMT2AALDH1A1MEN1GPR119 | |
| SCHEMBL24725739 | 0.78 | KMT2A (0.53) | MAPTKMT2AALDH1A1MEN1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481288-B1 | 1-Phenylpiperid-4-ylamines and drugs containing them | BASF AG (DE) | 1995-07-26 | — | — | EP | disclosed |
| US-5175174-A | PHENYLPIPERIDINYLAMINES AND DRUGS CONTAINING THESE | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0481288-A2 | 1-Phenylpiperid-4-ylamines and drugs containing them | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |