Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 8/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304730 | 0.84 | PREP (0.53) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL7302086 | 0.84 | PREP (0.77) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL7294777 | 0.84 | PREP (0.77) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL7297629 | 0.81 | PREP (0.76) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL7295355 | 0.80 | PREP (0.78) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL170116 | 0.74 | ACE (0.44) | ACECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL175453 | 0.74 | ACE (0.44) | ACECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7295850 | 0.74 | PREP (0.62) | PREPACECHRM2CHRM4CHRM1 | |
| SCHEMBL7303965 | 0.72 | PREP (0.66) | PREP | |
| SCHEMBL7303962 | 0.72 | PREP (0.66) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |