Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303343 | 0.84 | PREP (0.56) | PREPALDH1A1KMT2ASMN1; SMN2CHRM2 | |
| SCHEMBL7302086 | 0.81 | PREP (0.77) | PREPALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7294777 | 0.81 | PREP (0.77) | PREPALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7297629 | 0.78 | PREP (0.76) | PREPALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7295355 | 0.78 | PREP (0.78) | PREPALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL3504947 | 0.77 | HPGD (0.58) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL7475648 | 0.77 | HPGD (0.58) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL9372814 | 0.77 | HPGD (0.58) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL7295370 | 0.75 | PREP (0.71) | PREPALDH1A1L3MBTL1DPP4SMN1; SMN2 | |
| SCHEMBL7302899 | 0.74 | PREP (0.38) | PREPALDH1A1DPP4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |