Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687205 | 0.90 | GPR119 (0.60) | GPR119 | |
| SCHEMBL7331168 | 0.85 | GPR119 (0.62) | GPR119 | |
| SCHEMBL9686159 | 0.82 | GPR119 (0.64) | GPR119 | |
| SCHEMBL2590215 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2587691 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2583246 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL9686551 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL2583610 | 0.78 | GPR119 (1.00) | GPR119 | |
| SCHEMBL10520569 | 0.78 | GPR119 (0.60) | GPR119 | |
| SCHEMBL14760372 | 0.77 | GPR119 (0.81) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |