SCHEMBL9686159

SCHEMBL9686159

CC(C)C1CC(=O)NN=C1c1ccc2oc([N])nc2c1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9686163 0.90 GPR119 (0.60) GPR119
SCHEMBL7331168 0.85 GPR119 (0.62) GPR119
SCHEMBL7303499 0.82 GPR119 (0.64) GPR119
SCHEMBL2583079 0.78 GPR119 (1.00) GPR119
SCHEMBL7335403 0.78 GPR119 (0.56) GPR119
SCHEMBL9686166 0.75 GPR119 (0.55) GPR119
SCHEMBL7299065 0.75 PDE3B (0.55) GPR119
SCHEMBL9687281 0.74 GPR119 (0.59) GPR119
SCHEMBL7297977 0.74 GPR119 (0.52) GPR119
SCHEMBL9687496 0.73 GPR119 (0.53) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5135932-A 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE DR. KARL THOMAE GMBH (DE) 1992-08-04 US disclosed