Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285095 | 0.84 | HTR2A (0.65) | MEN1KMT2AHTR2A | |
| SCHEMBL30861230 | 0.84 | HTR2A (0.65) | MEN1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL31327595 | 0.83 | HTR2A (0.63) | MEN1KMT2AHTR2A | |
| SCHEMBL15957303 | 0.82 | LTA4H (0.57) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| SCHEMBL30148504 | 0.82 | MAOB (0.53) | L3MBTL1PPARAPPARGPPARDHTR2A | |
| SCHEMBL6036137 | 0.81 | HSD17B10 (0.68) | MEN1KMT2AL3MBTL1PPARAPPARG | |
| SCHEMBL8964099 | 0.80 | MMP1 (0.57) | KMT2AMMP1 | |
| SCHEMBL8964094 | 0.80 | MMP1 (0.57) | KMT2AMMP1 | |
| SCHEMBL421657 | 0.79 | BCHE (0.56) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A | |
| SCHEMBL421658 | 0.79 | BCHE (0.56) | LTA4HMEN1HSP90AA1HSP90AB1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | disclosed |