Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270255 | 1.00 | MEN1 (0.52) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9271864 | 0.99 | MEN1 (0.51) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL9273376 | 0.89 | MEN1 (0.52) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL7293128 | 0.88 | ITGB3 (0.54) | MEN1KMT2AHDAC1ITGB3ITGA2B | |
| SCHEMBL7297922 | 0.88 | ITGB3 (0.54) | MEN1KMT2AHDAC1ITGB3ITGA2B | |
| SCHEMBL7493453 | 0.87 | PRSS1 (0.58) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL9274240 | 0.86 | MAPT (0.52) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| Iodide SCHEMBL9261540 | 0.85 | MAPT (0.51) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL9268429 | 0.81 | PSMB5 (0.56) | MEN1KMT2AHTTPOLBSMN1; SMN2 | |
| SCHEMBL9261433 | 0.81 | PSMB5 (0.56) | MEN1KMT2AHTTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |