Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301925 | 0.96 | MMP2 (0.52) | LTA4HHTTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7301249 | 0.93 | ALDH1A1 (0.51) | HTTL3MBTL1ALDH1A1MAPK1MMP2 | |
| Hydrochloric Acid SCHEMBL17335911 | 0.92 | ALDH1A1 (0.50) | HTTL3MBTL1ALDH1A1MAPK1MMP2 | |
| Hydrochloric Acid SCHEMBL31258271 | 0.90 | ALDH1A1 (0.49) | HTTL3MBTL1ALDH1A1MAPK1MMP2 | |
| SCHEMBL20334484 | 0.89 | HDAC3 (0.50) | LTA4HHTTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL17599911 | 0.88 | EPHX2 (0.56) | HTTL3MBTL1ALDH1A1MMP2HDAC3 | |
| SCHEMBL7452946 | 0.88 | EPHX2 (0.56) | HTTL3MBTL1ALDH1A1MMP2HDAC3 | |
| SCHEMBL18703881 | 0.88 | EPHX2 (0.56) | HTTL3MBTL1ALDH1A1MMP2HDAC3 | |
| Hydrochloric Acid SCHEMBL23748118 | 0.88 | HDAC3 (0.49) | LTA4HHTTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL23518457 | 0.87 | ALDH1A1 (0.51) | LTA4HHTTL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |