Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 12/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049832 | 0.86 | GBA1 (0.36) | — | |
| SCHEMBL9049068 | 0.86 | GBA1 (0.36) | — | |
| SCHEMBL9049913 | 0.81 | PREP (0.30) | — | |
| SCHEMBL9047631 | 0.81 | GBA1 (0.39) | — | |
| SCHEMBL9049992 | 0.81 | GBA1 (0.39) | — | |
| SCHEMBL9047368 | 0.79 | GBA1 (0.42) | — | |
| SCHEMBL9049080 | 0.78 | PREP (0.36) | — | |
| SCHEMBL8155778 | 0.78 | PREP (0.36) | — | |
| SCHEMBL9049231 | 0.76 | PREP (0.32) | — | |
| SCHEMBL7302678 | 0.74 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |