Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 7/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049068 | 1.00 | GBA1 (0.36) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL9047631 | 0.94 | GBA1 (0.39) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL9049992 | 0.94 | GBA1 (0.39) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL9049913 | 0.93 | PREP (0.30) | PREP | |
| SCHEMBL9047368 | 0.93 | GBA1 (0.42) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL9049080 | 0.91 | PREP (0.36) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL8155778 | 0.91 | PREP (0.36) | GBA1ADRA1DADRA1AADRA1BPREP | |
| SCHEMBL9049231 | 0.87 | PREP (0.32) | PREP | |
| SCHEMBL7303597 | 0.86 | PNMT (0.41) | — | |
| SCHEMBL7291285 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |