Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17611975 | 0.84 | EPHX2 (0.31) | KMT2A | |
| SCHEMBL16028488 | 0.79 | CYP2C19 (0.49) | LMNACYP2C19 | |
| SCHEMBL16076177 | 0.79 | CYP2C19 (0.44) | LMNACYP2C19 | |
| SCHEMBL12329471 | 0.78 | CYP2C19 (0.51) | LMNACYP2C19 | |
| SCHEMBL24360999 | 0.75 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL15867799 | 0.75 | USP2 (0.33) | KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL23037193 | 0.75 | CYP2C19 (0.34) | LMNAKMT2ACYP2C19 | |
| SCHEMBL15867787 | 0.73 | DGAT1 (0.33) | KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL7296150 | 0.73 | CYP2C19 (0.37) | LMNACYP2C19 | |
| SCHEMBL16169952 | 0.73 | LMNA (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |