Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301679 | 0.84 | HTT (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7292348 | 0.83 | RAB9A (0.62) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12933205 | 0.81 | HTT (0.48) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7295317 | 0.80 | NR1H4 (0.58) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7292242 | 0.78 | RAB9A (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1275465 | 0.78 | MEN1 (0.48) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7296723 | 0.77 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1687869 | 0.77 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7300836 | 0.77 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2346973 | 0.76 | MAPT (0.62) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |