Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7303882 | 0.99 | LNPEP (0.56) | LNPEPSLC7A5ERAP2KDM5BIL1RN | |
| SCHEMBL10779210 | 0.83 | CYP1A2 (0.49) | LNPEPSLC7A5KDM5BNPC1HPGD | |
| SCHEMBL7300179 | 0.81 | KDM5B (0.45) | LNPEPSLC7A5KDM5BNPC1HPGD | |
| SCHEMBL7306530 | 0.80 | LNPEP (0.45) | LNPEPSLC7A5ERAP2KDM5BIL1RN | |
| SCHEMBL7295772 | 0.80 | TACR1 (0.54) | — | |
| SCHEMBL10708877 | 0.80 | SLC7A5 (0.64) | LNPEPSLC7A5ERAP2HPGDRAB9A | |
| SCHEMBL8120133 | 0.79 | SLC7A5 (0.56) | LNPEPSLC7A5ERAP2HPGDROCK2 | |
| SCHEMBL9138219 | 0.79 | IL1RN (0.44) | LNPEPSLC7A5ERAP2KDM5BIL1RN | |
| SCHEMBL9244629 | 0.79 | LNPEP (0.42) | LNPEPKDM5BIL1RNNPC1HPGD | |
| SCHEMBL9602121 | 0.79 | ANPEP (0.58) | SLC7A5NPC1RAB9ASMN1; SMN2CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636630-B1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON SPA (IT) | 1999-04-28 | — | — | EP | disclosed |
| US-5438046-A | Enzyme inhibitors | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0636630-A1 | N-heteroaryl substituted derivatives of propanamide useful in the treatment of cardiovascular diseases | ZAMBON GROUP S.p.A. (IT) | 1995-02-01 | — | — | EP | disclosed |