Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303717 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL7308981 | 0.86 | KDM4E (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL7308953 | 0.86 | KDM4E (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL7308986 | 0.86 | KDM4E (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL7300353 | 0.79 | MAPT (0.45) | SMN1; SMN2MAPTLMNAKDM4ENPC1 | |
| SCHEMBL8326536 | 0.79 | MAPT (0.45) | SMN1; SMN2MAPTLMNAKDM4ENPC1 | |
| SCHEMBL5722938 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL5722948 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL5722944 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2RECQLHIF1AEGFRPDGFRB | |
| SCHEMBL5723204 | 0.74 | ALDH1A1 (0.35) | SMN1; SMN2MAPTNPSR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819689-A1 | 5-substituted (2H) chromenes | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-01-21 | — | — | EP | disclosed |