Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305823 | 0.87 | TSHR (0.76) | TSHRPOLBGAAKDM4ECYP1A2 | |
| SCHEMBL7311114 | 0.86 | TSHR (0.75) | TSHRPOLBGAAKDM4EMAPK1 | |
| SCHEMBL4355668 | 0.84 | TSHR (0.73) | TSHRPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL31194571 | 0.82 | TSHR (0.70) | TSHRPOLBGAAKDM4ECYP1A2 | |
| SCHEMBL8916000 | 0.81 | TSHR (0.67) | TSHRPOLBGAAKDM4ECYP1A2 | |
| SCHEMBL23116895 | 0.81 | TSHR (0.68) | TSHRPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL6881906 | 0.81 | TSHR (0.68) | TSHRPOLBGAAKDM4ECYP1A2 | |
| SCHEMBL7297521 | 0.80 | TSHR (0.67) | TSHRPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL33942 | 0.79 | KDM4E (0.75) | TSHRPOLBGAAKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL7110274 | 0.78 | KDM4E (0.73) | TSHRPOLBGAAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |