Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303767 | 0.87 | TSHR (1.00) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL7311114 | 0.85 | TSHR (0.75) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL7297521 | 0.76 | TSHR (0.67) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL7301245 | 0.74 | TSHR (0.60) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL7302490 | 0.74 | TSHR (0.59) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL16832559 | 0.73 | KDM4E (0.73) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL7352542 | 0.71 | TSHR (0.56) | TSHRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL4355668 | 0.71 | TSHR (0.73) | TSHRKDM4EMAPTALDH1A1POLB | |
| SCHEMBL17963384 | 0.70 | POLB (0.71) | KDM4EMAPTPOLBGAAMEN1 | |
| SCHEMBL8552268 | 0.70 | TSHR (0.55) | TSHRKDM4EMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |