Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310143 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL7309439 | 0.90 | PPARG (0.60) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Hydrochloric Acid SCHEMBL7303166 | 0.90 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL7310636 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL8562435 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL7309505 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL8562433 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Hydrochloric Acid SCHEMBL8568424 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL8560944 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL7432496 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298763-B1 | METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8735598-B2 | Method for producing 1-biphenylmethylimidazole compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-27 | — | — | US | disclosed |
| US-8735598-B2 | Method for producing 1-biphenylmethylimidazole compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20110092713-A1 | METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-21 | — | — | US | disclosed |
| US-20110092713-A1 | METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2298763-A1 | METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092713-A1 | METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND | AGTR1, AGTR2, AOC3 | AGTR1 1/4885AGTR2 2/4885ABCC3 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.