Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 9/20 | 0.42 |
| ▸ | CPT1A | P50416 | 9/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297128 | 0.91 | CPT2 (0.44) | CPT2CPT1ASPHK2SPHK1ACE | |
| SCHEMBL7304579 | 0.89 | SPHK2 (0.43) | SPHK2SPHK1F2PLGACE | |
| SCHEMBL7302617 | 0.85 | ACE (0.45) | F2ACE | |
| SCHEMBL7298264 | 0.84 | ACE (0.45) | F2ACE | |
| SCHEMBL7296963 | 0.82 | ACE (0.40) | SPHK2SPHK1ACEKMT2AKLK7 | |
| SCHEMBL7302798 | 0.79 | SPHK2 (0.44) | SPHK2SPHK1ACEKMT2AKLK7 | |
| SCHEMBL7302058 | 0.76 | KLK7 (0.45) | F2KDM4ELMNAKMT2AKLK7 | |
| SCHEMBL7298606 | 0.76 | FKBP4 (0.41) | — | |
| SCHEMBL7338057 | 0.76 | ACE (0.38) | F2ACEKMT2AKLK7 | |
| SCHEMBL7324515 | 0.76 | ACE (0.46) | F2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |