Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296963 | 0.91 | ACE (0.40) | SPHK2SPHK1DPP4DPP8DPP9 | |
| SCHEMBL7304579 | 0.90 | SPHK2 (0.43) | SPHK2SPHK1DPP4DPP8DPP9 | |
| SCHEMBL7297128 | 0.88 | CPT2 (0.44) | SPHK2SPHK1DPP4DPP8DPP9 | |
| SCHEMBL7302058 | 0.88 | KLK7 (0.45) | CTRB1FKBP1APREPKMT2ACTSK | |
| SCHEMBL7338057 | 0.84 | ACE (0.38) | DPP4DPP8DPP9DPP7OPRM1 | |
| SCHEMBL7324515 | 0.84 | ACE (0.46) | FKBP1AACE | |
| SCHEMBL7297651 | 0.82 | ITGB3 (0.47) | DPP4DPP8OPRM1OPRD1ACE | |
| SCHEMBL7305461 | 0.80 | HTR2C (0.39) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7303956 | 0.79 | CPT2 (0.42) | SPHK2SPHK1HDAC1CTRB1KMT2A | |
| SCHEMBL7293906 | 0.79 | FKBP4 (0.39) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |