Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900857 | 0.78 | PARP1 (0.43) | PARP1 | |
| SCHEMBL7692011 | 0.78 | PARP1 (0.48) | PARP1 | |
| SCHEMBL7689606 | 0.73 | RXFP1 (0.44) | PARP1 | |
| SCHEMBL8726015 | 0.73 | — | — | |
| SCHEMBL8726013 | 0.73 | — | — | |
| SCHEMBL1043235 | 0.72 | — | — | |
| SCHEMBL14353675 | 0.70 | ALDH1A1 (0.48) | PARP1 | |
| SCHEMBL5254656 | 0.68 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL2548078 | 0.68 | HPRT1 (0.64) | — | |
| SCHEMBL603488 | 0.68 | HPRT1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |