Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200259 | 0.84 | CTRC (0.39) | CTRCTYRHTTHPGDNPC1 | |
| SCHEMBL30044969 | 0.84 | TYR (0.50) | CTRCTYRHTTHPGDNPC1 | |
| SCHEMBL4633219 | 0.84 | TYR (0.50) | CTRCTYRHTTHPGDNPC1 | |
| SCHEMBL7305833 | 0.82 | PRKCI (0.37) | HPGDRAB9AALDH1A1KDM4EELANE | |
| SCHEMBL1004924 | 0.81 | CTRC (0.42) | CTRCTYRHTTHPGDNPC1 | |
| SCHEMBL201763 | 0.77 | BID (0.44) | CTRCTYRCYP3A4ALOX5GABRA1 | |
| SCHEMBL458858 | 0.77 | TYR (0.41) | CTRCTYRHTTHPGDNPC1 | |
| SCHEMBL1133572 | 0.77 | TYR (0.53) | CTRCTYRHTTMAPTMEN1 | |
| SCHEMBL31230428 | 0.77 | TYR (0.53) | CTRCTYRHTTMAPTMEN1 | |
| SCHEMBL6560504 | 0.76 | TYR (0.44) | CTRCTYRHTTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |