Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304182 | 0.82 | CTRC (0.43) | KDM4EALDH1A1HPGDELANECTSG | |
| SCHEMBL1711830 | 0.82 | KDM4E (0.39) | PRKCIKDM4EALDH1A1HPGDGAA | |
| Ammonia Solution, Strong SCHEMBL5848979 | 0.79 | KDM4E (0.38) | PRKCIKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1007884 | 0.79 | PRKCI (0.36) | PRKCIKDM4EALDH1A1HPGDGAA | |
| SCHEMBL3569674 | 0.77 | KDM4E (0.37) | KDM4EALDH1A1HPGDGAAELANE | |
| SCHEMBL8089551 | 0.76 | PRKCI (0.37) | PRKCIKDM4EALDH1A1HPGDGAA | |
| SCHEMBL7309326 | 0.75 | GABRA1 (0.44) | PRKCIELANECTSG | |
| SCHEMBL4077011 | 0.75 | PRKCI (0.39) | PRKCIKDM4EALDH1A1HPGDGAA | |
| SCHEMBL28277298 | 0.74 | ALDH1A1 (0.36) | PRKCIKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1005994 | 0.73 | GABRA1 (0.38) | KDM4EALDH1A1HPGDGAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |