Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311684 | 0.95 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8332201 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL61 | 0.90 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL28491030 | 0.88 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL668602 | 0.88 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL962 | 0.87 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9558700 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL7305879 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7363748 | 0.87 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL28498803 | 0.86 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |