Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118878 | 0.95 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8469323 | 0.92 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL61 | 0.91 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL7304283 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL28491030 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL668602 | 0.88 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9558700 | 0.88 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL7305879 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL28498803 | 0.87 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL855 | 0.87 | AGTR1 (0.64) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962500-A | HYPOSENSITVE AGENT | MERCK SHARP & DOHME CORP. | 1999-10-05 | — | — | US | disclosed |