Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294739 | 0.90 | KMT2A (0.46) | KMT2AACECTRB1ALDH1A1CYP3A4 | |
| SCHEMBL7295927 | 0.88 | F2 (0.49) | KMT2ACASP1F2PLGACE | |
| SCHEMBL7302872 | 0.86 | ACE (0.44) | KMT2ACASP1F2PLGACE | |
| SCHEMBL7297974 | 0.83 | ACE (0.42) | KMT2ACASP1F2PLGACE | |
| SCHEMBL7304387 | 0.83 | ACE (0.46) | KMT2ACASP1F2PLGACE | |
| SCHEMBL7298055 | 0.81 | F2 (0.61) | CASP1F2PLGCTRB1PRCP | |
| SCHEMBL7296144 | 0.80 | F2 (0.43) | CASP1F2PLGACECTRB1 | |
| SCHEMBL7295597 | 0.80 | F2 (0.48) | CASP1F2PLGACECTRB1 | |
| SCHEMBL7393398 | 0.79 | F2 (0.47) | F2PLGDPP4DPP8DPP7 | |
| SCHEMBL7303446 | 0.78 | TGM2 (0.48) | KMT2ACASP1F2PLGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | disclosed |