Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7304917 | 0.82 | NOTUM (0.47) | NOTUMCHRM3CHRM2CHRM1 | |
| Maleic Acid SCHEMBL7304911 | 0.82 | NOTUM (0.47) | NOTUMCHRM3CHRM2CHRM1 | |
| Fumaric Acid SCHEMBL7296355 | 0.80 | NOTUM (0.46) | NOTUMCHRM3CHRM2CHRM1 | |
| Maleic Acid SCHEMBL7296350 | 0.80 | NOTUM (0.46) | NOTUMCHRM3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7304999 | 0.80 | NOTUM (0.48) | NOTUMCNR2BIRC2HTR3EHTR3B | |
| Ricasetron SCHEMBL634827 | 0.79 | NOTUM (0.52) | NOTUMCNR2HTR3A | |
| Ricasetron SCHEMBL21715163 | 0.79 | NOTUM (0.52) | NOTUMCNR2HTR3A | |
| Ricasetron SCHEMBL634826 | 0.79 | NOTUM (0.52) | NOTUMCNR2HTR3A | |
| Ricasetron SCHEMBL20362251 | 0.79 | NOTUM (0.52) | NOTUMCNR2HTR3A | |
| Ricasetron SCHEMBL7445859 | 0.78 | NOTUM (0.51) | NOTUMCNR2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403882-A2 | Indole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |