Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313411 | 0.92 | ALDH1A1 (0.57) | NPC1RAB9A | |
| SCHEMBL2476769 | 0.92 | ALDH1A1 (0.57) | NPC1RAB9A | |
| SCHEMBL5740768 | 0.92 | ALDH1A1 (0.57) | NPC1RAB9A | |
| SCHEMBL5701961 | 0.82 | CA2 (0.54) | HPGD | |
| SCHEMBL7067688 | 0.82 | CA2 (0.54) | HPGD | |
| SCHEMBL5701920 | 0.82 | CA2 (0.54) | HPGD | |
| SCHEMBL7879782 | 0.81 | CA2 (0.52) | HPGD | |
| SCHEMBL5702038 | 0.80 | HPGD (0.54) | TSHRHPGDMEN1KMT2A | |
| SCHEMBL5702058 | 0.80 | HPGD (0.54) | TSHRHPGDMEN1KMT2A | |
| Water SCHEMBL7879777 | 0.80 | CA2 (0.51) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |