⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304755 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL18755136 | 0.72 | GLA (0.38) | — | |
| SCHEMBL19287370 | 0.71 | — | — | |
| SCHEMBL1426674 | 0.70 | — | — | |
| SCHEMBL452003 | 0.69 | HCAR2 (0.38) | — | |
| SCHEMBL452002 | 0.69 | HCAR2 (0.38) | — | |
| SCHEMBL2030189 | 0.69 | — | — | |
| SCHEMBL14527700 | 0.68 | — | — | |
| SCHEMBL22779641 | 0.68 | CCNC (0.31) | — | |
| SCHEMBL8072668 | 0.67 | KMT2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834433-A | ANTITUMOR AND -CARCINOMA AGENTS; SMALL CELL LUNG AND PROSTATIC CARCINOMA; ANTIMIOTIC AND ANTISECRETORY AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0421367-B1 | Anticoagulant peptides | MERRELL PHARMA INC (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0585397-B1 | BOMBESIN ANALOGS | MERRELL PHARMA INC (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0434979-B1 | Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide | MERRELL DOW PHARMA (US) | 1996-01-03 | — | — | EP | disclosed |
| EP-0421366-B1 | Radiolabeled anticoagulant peptides | MERRELL DOW PHARMA (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5428018-A | Antagonist; hormone inhibitor | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5428019-A | Digestive system disorders; antitumor agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0626973-A1 | PHENYLALANINE ANALOGS OF BOMBESIN | MERRELL PHARMACEUTICALS INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| EP-0585397-A1 | BOMBESIN ANALOGS. | MERRELL DOW PHARMA (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5279812-A | Polypeptide; amino acid sequence of hirudin | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-01-18 | — | — | US | disclosed |
| WO-1993016105-A1 | PHENYLALANINE ANALOGS OF BOMBESIN | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| WO-1992020707-A1 | BOMBESIN ANALOGS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0468497-A2 | Peptide-antagonists of bombesin/GRP | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0434979-A1 | Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0421366-A1 | Radiolabeled anticoagulant peptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0421367-A1 | Anticoagulant peptides | MERRELL PHARMACEUTICALS INC. (US) | 1991-04-10 | — | — | EP | disclosed |