Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TXN | P10599 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013494 | 0.78 | ALOX15 (0.41) | TAAR1ALOX15HTR1ATERTFDPS | |
| SCHEMBL7274747 | 0.77 | TAAR1 (0.47) | TAAR1ALOX15HTR1ATERTTXN | |
| SCHEMBL1970139 | 0.74 | ALOX15 (0.41) | TAAR1ALOX15HTR1ATERTFDPS | |
| SCHEMBL1971765 | 0.74 | ALOX15 (0.41) | TAAR1ALOX15HTR1ATERTFDPS | |
| Hydrochloric Acid SCHEMBL3949887 | 0.73 | ALOX15 (0.40) | TAAR1ALOX15HTR1ATERTFDPS | |
| SCHEMBL1665687 | 0.72 | — | — | |
| SCHEMBL233107 | 0.71 | — | — | |
| SCHEMBL4775871 | 0.71 | ALOX15 (0.45) | TAAR1ALOX15HTR1ATERTFDPS | |
| SCHEMBL10654795 | 0.71 | — | — | |
| SCHEMBL18457197 | 0.70 | FDPS (0.37) | TAAR1ALOX15HTR1ATERTFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |