Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285659 | 0.86 | REN (0.49) | RENBACE1CTSD | |
| SCHEMBL7285655 | 0.86 | REN (0.49) | RENBACE1CTSD | |
| SCHEMBL9876339 | 0.71 | REN (0.63) | REN | |
| SCHEMBL10731177 | 0.71 | REN (0.55) | REN | |
| SCHEMBL10868633 | 0.71 | REN (0.55) | REN | |
| SCHEMBL9876318 | 0.71 | REN (0.62) | REN | |
| SCHEMBL9876316 | 0.71 | REN (0.62) | REN | |
| SCHEMBL10458253 | 0.71 | REN (0.62) | REN | |
| SCHEMBL9755323 | 0.70 | REN (0.57) | RENCTSD | |
| SCHEMBL10763181 | 0.70 | REN (0.64) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |