Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.49 |
| ▸ | BACE1 | P56817 | 8/20 | 0.49 |
| ▸ | CTSD | P07339 | 5/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285659 | 1.00 | REN (0.49) | RENBACE1CTSDPTPN1 | |
| SCHEMBL7304761 | 0.86 | REN (0.44) | RENBACE1CTSD | |
| SCHEMBL10977797 | 0.79 | REN (0.57) | REN | |
| SCHEMBL10977795 | 0.79 | REN (0.57) | REN | |
| SCHEMBL7288779 | 0.76 | GPR34 (0.53) | REN | |
| SCHEMBL9755318 | 0.76 | REN (0.57) | RENCTSDPTPN1 | |
| SCHEMBL7292530 | 0.76 | ALDH1A1 (0.58) | REN | |
| SCHEMBL10731177 | 0.75 | REN (0.55) | REN | |
| SCHEMBL10868633 | 0.75 | REN (0.55) | REN | |
| SCHEMBL7370152 | 0.74 | REN (0.56) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |