Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 6/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352795 | 0.86 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL12187263 | 0.85 | ALDH1A1 (0.38) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL14750440 | 0.85 | CYP2D6 (0.38) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL10893754 | 0.83 | TSHR (0.45) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL1132299 | 0.81 | TSHR (0.43) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL9818536 | 0.81 | TSHR (0.43) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL89067 | 0.81 | TSHR (0.43) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL56555 | 0.81 | TSHR (0.43) | TSHRALDH1A1MAPK1ANPEPDNPEP | |
| SCHEMBL12346197 | 0.80 | LMNA (0.39) | TSHRALDH1A1MAPK1ANPEPSLC7A5 | |
| Hydrochloric Acid SCHEMBL7269763 | 0.77 | GMNN (0.38) | TSHRALDH1A1MAPK1ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063208-A | Cardiovascular disorders, vision defects | ABBOTT LABORATORIES (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |