Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306809 | 0.96 | ITGB3 (0.70) | ITGB3ITGA2BMAPK1HDAC3HDAC4 | |
| SCHEMBL7307289 | 0.92 | ITGB3 (0.70) | ITGB3ITGA2BMAPK1 | |
| Hydrochloric Acid SCHEMBL8408094 | 0.85 | MAPK1 (0.68) | ITGB3ITGA2BMAPK1HDAC3HDAC4 | |
| SCHEMBL7328394 | 0.85 | MAPK1 (0.63) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL8407980 | 0.84 | F10 (0.60) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL5540645 | 0.84 | MAPK1 (0.58) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL7389300 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL14599582 | 0.82 | MAPK1 (0.61) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL14599527 | 0.82 | MAPK1 (0.61) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL14599618 | 0.82 | MAPK1 (0.61) | ITGB3ITGA2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |