Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 11/20 | 0.38 |
| ▸ | BIRC3 | Q13489 | 9/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 9/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317417 | 1.00 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7305036 | 1.00 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7305045 | 1.00 | XIAP (0.38) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL8083547 | 0.85 | TACR1 (0.44) | XIAPBIRC3BIRC2ACECFD | |
| SCHEMBL7308390 | 0.85 | TACR1 (0.44) | XIAPBIRC3BIRC2ACECFD | |
| SCHEMBL7308379 | 0.85 | TACR1 (0.44) | XIAPBIRC3BIRC2ACECFD | |
| SCHEMBL7308559 | 0.84 | EBP (0.36) | XIAPBIRC3BIRC2EBPSIGMAR1 | |
| SCHEMBL7308566 | 0.84 | EBP (0.36) | XIAPBIRC3BIRC2EBPSIGMAR1 | |
| SCHEMBL7314971 | 0.84 | XIAP (0.36) | XIAPBIRC3BIRC2ACECTSS | |
| SCHEMBL7314975 | 0.84 | XIAP (0.36) | XIAPBIRC3BIRC2ACECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |