Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 7/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 7/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 7/20 | 0.34 |
| ▸ | CFD | P00746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308559 | 1.00 | EBP (0.36) | EBPSIGMAR1XIAPBIRC3BIRC2 | |
| SCHEMBL7305041 | 0.84 | XIAP (0.38) | EBPSIGMAR1XIAPBIRC3BIRC2 | |
| SCHEMBL7305036 | 0.84 | XIAP (0.38) | EBPSIGMAR1XIAPBIRC3BIRC2 | |
| SCHEMBL7305045 | 0.84 | XIAP (0.38) | EBPSIGMAR1XIAPBIRC3BIRC2 | |
| SCHEMBL7317417 | 0.84 | XIAP (0.38) | EBPSIGMAR1XIAPBIRC3BIRC2 | |
| SCHEMBL8083547 | 0.81 | TACR1 (0.44) | XIAPBIRC3BIRC2CFDDPP4 | |
| SCHEMBL7308379 | 0.81 | TACR1 (0.44) | XIAPBIRC3BIRC2CFDDPP4 | |
| SCHEMBL7308390 | 0.81 | TACR1 (0.44) | XIAPBIRC3BIRC2CFDDPP4 | |
| SCHEMBL7309067 | 0.75 | ACE (0.41) | GAADPP4DPP8 | |
| SCHEMBL7309074 | 0.75 | ACE (0.41) | GAADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |