Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299332 | 0.84 | KMT2A (0.44) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7302037 | 0.81 | KMT2A (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11868080 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7300113 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7955916 | 0.77 | DPP4 (0.47) | ALDH1A1TAAR1IDO1DPP4 | |
| SCHEMBL3131950 | 0.77 | DPP4 (0.47) | ALDH1A1TAAR1IDO1DPP4 | |
| SCHEMBL5225287 | 0.77 | DPP4 (0.47) | ALDH1A1TAAR1IDO1DPP4 | |
| SCHEMBL7303337 | 0.77 | CYP2D6 (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7305729 | 0.76 | KIF11 (0.44) | SMN1; SMN2ALDH1A1KMT2ATAAR1IDO1 | |
| SCHEMBL27514919 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |