Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025140 | 0.80 | HTT (0.43) | IDO1TAAR1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11860377 | 0.79 | KIF11 (0.49) | KIF11SMN1; SMN2KMT2A | |
| SCHEMBL11860380 | 0.79 | KIF11 (0.49) | KIF11SMN1; SMN2KMT2A | |
| SCHEMBL5696521 | 0.79 | IDO1 (0.50) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28403191 | 0.78 | IDO1 (0.55) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10411195 | 0.78 | IDO1 (0.51) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7305059 | 0.76 | SMN1; SMN2 (0.42) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7969377 | 0.74 | IDO1 (0.53) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22200354 | 0.74 | IDO1 (0.52) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10994379 | 0.74 | KMT2A (0.39) | IDO1TAAR1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |