Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95119 | 0.75 | ALDH1A1 (0.47) | KMT2AHTTMEN1LMNAKDM4E | |
| SCHEMBL3531494 | 0.74 | NQO2 (0.45) | KDRKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7307217 | 0.73 | ALDH1A1 (0.47) | KMT2AHTTMEN1LMNAMAPT | |
| SCHEMBL9427593 | 0.72 | TLR9 (0.54) | TLR9MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL5341033 | 0.72 | KDM4E (0.55) | TLR9MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL13954226 | 0.70 | ALDH1A1 (0.61) | TLR9MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL28853094 | 0.69 | TLR9 (0.81) | TLR9KMT2AATMMEN1LMNA | |
| SCHEMBL3480837 | 0.69 | KMT2A (0.67) | TLR9EGFRKMT2AATMHTT | |
| SCHEMBL29922808 | 0.69 | KMT2A (0.67) | TLR9EGFRKMT2AATMHTT | |
| SCHEMBL4586206 | 0.69 | KMT2A (0.67) | TLR9EGFRKMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |