Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | PPARA | Q07869 | 9/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731734 | 0.84 | LOXL2 (0.49) | PPARGPPARAPPARD | |
| SCHEMBL617014 | 0.83 | MAPT (0.52) | NR1H4EPHX2PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL5846568 | 0.83 | LOXL2 (0.47) | PPARGPPARAPPARD | |
| SCHEMBL20713777 | 0.83 | CYP4A11 (0.47) | PPARGPPARAPPARDCA2 | |
| SCHEMBL20713748 | 0.82 | PPARG (0.41) | PPARGPPARAPPARDCA2HDAC1 | |
| SCHEMBL7158402 | 0.82 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL8382918 | 0.81 | ATM (0.48) | NR1H4EPHX2ITGB3ITGA2BCA2 | |
| SCHEMBL27994504 | 0.81 | SMN1; SMN2 (0.50) | NR1H4EPHX2PPARGPPARAITGB3 | |
| SCHEMBL15149335 | 0.80 | MIF (0.48) | PPARGPPARAPPARDCA2 | |
| SCHEMBL7438712 | 0.79 | ADRB2 (0.40) | EPHX2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561112-A | ADMINISTERING SMALL SYNTHETIC PEPTIDES(SIMILAR TO GLYCINE-ASPARTIC ACID) TO SUPPRESS THROMBOSIS | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| EP-0560730-B1 | New derivatives of beta-amino acids with anti-thrombotic activity | SANDOZ LTD (CH) | 1996-09-11 | — | — | EP | disclosed |
| EP-0560730-A2 | New derivatives of beta-amino acids with anti-thrombotic activity | SANDOZ LTD. (CH) | 1993-09-15 | — | — | EP | disclosed |