Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315071 | 0.88 | KMT2A (0.44) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL466933 | 0.88 | KMT2A (0.44) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL466934 | 0.88 | KMT2A (0.44) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL467146 | 0.87 | KMT2A (0.43) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL467145 | 0.87 | KMT2A (0.43) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8419734 | 0.87 | KMT2A (0.43) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7311725 | 0.87 | KMT2A (0.43) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL7314254 | 0.86 | DRD2 (0.43) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL7313425 | 0.86 | DRD2 (0.39) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Sulfuric Acid SCHEMBL7308229 | 0.84 | KMT2A (0.43) | HTR2ADRD2HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839805-B1 | Pyrrolidinone derivatives and their use as antipsychotic medicaments | SCHERING AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-5969138-A | ANTIPSYCHOTIC AGENTS | MITSUI CHEMICALS, INC. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0839805-A1 | Pyrrolidinone derivatives and their use as antipsychotic medicaments | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-06 | — | — | EP | disclosed |