SCHEMBL7305742

SCHEMBL7305742

C=c1c(=O)[nH]c2n1Cc1cc(C)cc(OCCCCCC(C(N)=O)N3CCCC3)c1N=2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7305746 0.81 PDE3B (0.42) PDE3BPDE3A
SCHEMBL7320349 0.80 PDE3B (0.37) PDE3BPDE3A
SCHEMBL7316653 0.77 PDE3B (0.40) PDE3BPDE3A
SCHEMBL7312432 0.74 PDE3B (0.45) PDE3BPDE3A
SCHEMBL7318831 0.74 PDE3B (0.56) PDE3BPDE3A
SCHEMBL7307441 0.73 PDE3B (0.57) PDE3BPDE3A
SCHEMBL7308793 0.73 PDE3B (0.68) PDE3BPDE3A
SCHEMBL7314546 0.67 PDE3B (0.39) PDE3BPDE3A
SCHEMBL7320282 0.67 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7310612 0.66 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed