SCHEMBL7316653

SCHEMBL7316653

Cc1cc2c(c(OCCCCCC(C(N)=O)N3CCCC3)c1)N=C1NC(=O)C(CO)N1C2

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 11/20 0.40
PDE3A Q14432 11/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7316661 0.82 PDE3B (0.45) PDE3BPDE3A
SCHEMBL7313656 0.81 PDE3B (0.40) PDE3BPDE3A
SCHEMBL7305742 0.77 PDE3B (0.37) PDE3BPDE3A
SCHEMBL7309032 0.76 PDE3B (0.58) PDE3BPDE3A
SCHEMBL7307753 0.75 PDE3B (0.48) PDE3BPDE3A
SCHEMBL7312180 0.75 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7311705 0.75 PDE3B (0.70) PDE3BPDE3A
SCHEMBL7317560 0.69 PDE3B (0.56) PDE3BPDE3A
SCHEMBL7315285 0.69 PDE3B (0.41) PDE3BPDE3A
SCHEMBL7320601 0.67 PDE3B (0.35) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed