Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683255 | 1.00 | CAPN1 (0.43) | CAPN1CTSKCTSLCTSB | |
| SCHEMBL7305812 | 1.00 | CAPN1 (0.43) | CAPN1CTSKCTSLCTSB | |
| SCHEMBL7305799 | 1.00 | CAPN1 (0.43) | CAPN1CTSKCTSLCTSB | |
| SCHEMBL7438387 | 0.98 | CAPN1 (0.44) | CAPN1CTSK | |
| SCHEMBL7438374 | 0.98 | CAPN1 (0.44) | CAPN1CTSK | |
| SCHEMBL7438392 | 0.98 | CAPN1 (0.44) | CAPN1CTSK | |
| SCHEMBL7438369 | 0.98 | CAPN1 (0.44) | CAPN1CTSK | |
| SCHEMBL7437245 | 0.90 | CAPN1 (0.46) | CAPN1CTSK | |
| SCHEMBL7437237 | 0.90 | CAPN1 (0.46) | CAPN1CTSK | |
| SCHEMBL7305805 | 0.89 | MGLL (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |