Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305883 | 1.00 | PNMT (0.46) | PNMTADRA2AHSP90AA1KMT2AMAPT | |
| SCHEMBL30709850 | 0.76 | PNMT (0.65) | PNMTADRA2AKMT2AMAPTMEN1 | |
| SCHEMBL9483063 | 0.76 | PNMT (0.65) | PNMTADRA2AKMT2AMAPTMEN1 | |
| SCHEMBL1870205 | 0.73 | PNMT (0.54) | PNMTADRA2AHSP90AA1KMT2AMAPT | |
| SCHEMBL7320861 | 0.72 | MAPT (0.64) | HSP90AA1MAPTRAB9ALMNACA1 | |
| SCHEMBL7320868 | 0.72 | MAPT (0.64) | HSP90AA1MAPTRAB9ALMNACA1 | |
| SCHEMBL7402148 | 0.72 | PNMT (0.49) | PNMTADRA2AHSP90AA1KMT2AMAPT | |
| SCHEMBL15572533 | 0.71 | KMT2A (0.36) | HSP90AA1KMT2AMAPTMEN1RAB9A | |
| Ammonia Solution, Strong SCHEMBL27905491 | 0.70 | LMNA (0.62) | PNMTADRA2AHSP90AA1KMT2AMAPT | |
| SCHEMBL3407311 | 0.70 | MAPT (0.46) | PNMTADRA2AHSP90AA1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |