Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | CPT2 | P23786 | 6/20 | 0.43 |
| ▸ | CPT1A | P50416 | 6/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305931 | 1.00 | PREP (0.48) | PREPF2CPT2CPT1AACE | |
| SCHEMBL9097367 | 0.94 | ACE (0.49) | PREPF2ACE | |
| SCHEMBL9097372 | 0.94 | ACE (0.49) | PREPF2ACE | |
| SCHEMBL9097291 | 0.93 | F2 (0.49) | PREPF2CPT2CPT1AACE | |
| SCHEMBL9097297 | 0.93 | F2 (0.49) | PREPF2CPT2CPT1AACE | |
| SCHEMBL7297472 | 0.93 | PREP (0.48) | PREPF2ACEABCB1DPP4 | |
| SCHEMBL7297465 | 0.93 | PREP (0.48) | PREPF2ACEABCB1DPP4 | |
| SCHEMBL9096799 | 0.88 | CPT2 (0.56) | CPT2CPT1A | |
| SCHEMBL9096792 | 0.88 | CPT2 (0.56) | CPT2CPT1A | |
| SCHEMBL9096507 | 0.86 | CPT2 (0.44) | PREPCPT2CPT1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |