Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097372 | 1.00 | ACE (0.49) | ACEPREPF2YAP1LTA4H | |
| SCHEMBL7305938 | 0.94 | PREP (0.48) | ACEPREPF2 | |
| SCHEMBL7305931 | 0.94 | PREP (0.48) | ACEPREPF2 | |
| SCHEMBL7297472 | 0.92 | PREP (0.48) | ACEPREPF2TSHR | |
| SCHEMBL9097291 | 0.92 | F2 (0.49) | ACEPREPF2 | |
| SCHEMBL7297465 | 0.92 | PREP (0.48) | ACEPREPF2TSHR | |
| SCHEMBL9097297 | 0.92 | F2 (0.49) | ACEPREPF2 | |
| SCHEMBL9097668 | 0.83 | ACE (0.50) | ACEPREPF2YAP1LTA4H | |
| SCHEMBL9097660 | 0.83 | ACE (0.50) | ACEPREPF2YAP1LTA4H | |
| SCHEMBL7305097 | 0.83 | PREP (0.68) | PREPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |