Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.33 |
| ▸ | CDC14B | O60729 | 1/20 | 0.33 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18244061 | 0.77 | KIF11 (0.37) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL18241857 | 0.77 | KDM4E (0.43) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL7181355 | 0.75 | KDM4E (0.38) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL7297470 | 0.74 | KDM4E (0.40) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL5248582 | 0.72 | AXL (0.35) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL7306542 | 0.72 | KDM4E (0.38) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL12473229 | 0.71 | AXL (0.47) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL12310598 | 0.71 | AXL (0.47) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL15933714 | 0.69 | AXL (0.32) | AXLPOLBGAA | |
| SCHEMBL7302829 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |