Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311184 | 0.88 | BLM (0.41) | BLMTSHRSIGMAR1 | |
| SCHEMBL7305028 | 0.85 | BLM (0.51) | BLMTSHR | |
| SCHEMBL6268863 | 0.84 | HTR2A (0.53) | SLC6A2SLC6A4HTR2AHRH1BLM | |
| SCHEMBL9334169 | 0.84 | HTR2A (0.53) | SLC6A2SLC6A4HTR2AHRH1BLM | |
| SCHEMBL8159949 | 0.84 | HTR2A (0.53) | SLC6A2SLC6A4HTR2AHRH1BLM | |
| SCHEMBL7314540 | 0.83 | BLM (0.42) | BLMTSHR | |
| SCHEMBL7304998 | 0.82 | BCHE (0.45) | BLMTSHR | |
| SCHEMBL7311330 | 0.81 | BLM (0.49) | BLMTSHR | |
| SCHEMBL7312242 | 0.79 | LTB4R (0.51) | SLC6A2SLC6A4HTR2AHRH1HTR2C | |
| SCHEMBL8152258 | 0.77 | SLC6A2 (0.54) | SLC6A2SLC6A4HTR2AHRH1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581677-B1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | JOUVEINAL INST RECH (FR) | 1997-01-08 | — | — | EP | disclosed |
| US-5326784-A | Psychological and gastrointestinal disorders | INSTITUT DE RECHERCHE JOUVEINAL (FR) | 1994-07-05 | — | — | US | disclosed |
| EP-0581677-A1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1994-02-02 | — | — | EP | disclosed |