Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 10/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | IL6ST | P40189 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501460 | 0.88 | NAAA (0.48) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL3097863 | 0.88 | NAAA (0.45) | NAAAIDH1FAAHPPARAHDAC1 | |
| SCHEMBL46356 | 0.88 | NAAA (0.48) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL15586928 | 0.88 | NAAA (0.45) | NAAAIDH1FAAHPPARAHDAC1 | |
| SCHEMBL2501454 | 0.88 | NAAA (0.48) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL5662777 | 0.87 | CACNA1G (0.40) | NAAAIDH1FAAHHDAC1 | |
| SCHEMBL7346791 | 0.87 | NAAA (0.47) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL1915643 | 0.87 | NAAA (0.47) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL1915646 | 0.87 | NAAA (0.47) | NAAAIDH1FAAHPPARAIL6ST | |
| SCHEMBL548889 | 0.87 | NAAA (0.50) | NAAAIDH1FAAHPPARAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| EP-0465369-B1 | N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1994-04-13 | — | — | EP | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |
| EP-0465369-A1 | N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1992-01-08 | — | — | EP | disclosed |