Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297131 | 0.94 | MCHR1 (0.54) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7298689 | 0.86 | ITGB3 (0.58) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7299155 | 0.86 | ITGB3 (0.75) | MCHR1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7315353 | 0.85 | ITGB3 (0.74) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7302786 | 0.85 | ITGB3 (0.65) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7297084 | 0.83 | ITGB3 (0.56) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7322446 | 0.83 | MCHR1 (0.49) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7312182 | 0.83 | MCHR1 (0.54) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7389156 | 0.83 | ITGB3 (0.55) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7298306 | 0.83 | ITGB3 (0.54) | MCHR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8231486-A | — | — | None | — | — | JP | disclosed |
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |
| JP-H08231486-A | BICYCLIC COMPOUND AND BLOOD PLATELET COAGULATION INHIBITOR CONTAINING THE SAME | MITSUI TOATSU CHEM INC | 1996-09-10 | — | — | JP | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |